Oxidative DNA damage and embryo development
نویسندگان
چکیده
منابع مشابه
OGG1 DNA Repair Gene Polymorphism As a Biomarker of Oxidative and Genotoxic DNA Damage
Background: Single nucleotide polymorphisms in 8-oxoguanine DNA glycosylase-1 (OGG1) gene modulates DNA repair capacity and functions as one of the first lines of protective mechanisms against 8-hydroxy-2’-deoxyguanosine (8-OHdG) mutagenicity. OGG1-Cys326 gene polymorphism may decrease DNA repair function, causing oxidative stress due to higher oxidative DNA damage. The main purpose of this stu...
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ژورنال
عنوان ژورنال: Nature Medicine
سال: 1999
ISSN: 1078-8956,1546-170X
DOI: 10.1038/10420